In this study, the influence of Uno on both emotions and relationships was assessed. Several games were analyzed and the emotions were measured and evaluated with fMRIs, Polygraph tests and nonverbal communication. Data trends point to the production of positive Hyper Emotions, specifically happiness, for the winners and negative HEs, specifically hatred, for the losers. Analysis of the non-verbal communication along with the images from the fMRI scans ​confirms this analysis by showing that emotional state levels rose overall as the game progressed. Moreover, fMRI scans reveal that neural and chemical activities in the brain were much more apparent among the players that lost as compared to those who won.

While the happiness among winners in collaborative games along with positive nonverbal communication such as high fives and fist bumps points to relationships strengthening when teamwork was allowed, the majority of the data suggests that Uno generally ruins friendships. Still, much remains to be discovered about the tremendous impact of Uno on the brain, emotions, and relationships.

The scope of this experiment was limited to 5 trials with a fixed number of players and conducted with standard Uno rules. However, two of the aspects of Uno that contribute to its universal popularity is that it accommodates varying numbers of participants and it is highly customizable based on the desires of the players.

Thus, future research could be conducted with an increased number of trials. In addition, trials with different numbers of participants, in varied settings, and with varied rules, may offer more insight on the role of Uno in both emotions and relationships. Perhaps the game of Uno can have therapeutic purposes as well. By having a specialized version of Uno where everyone wins in some way or another can possibly reduce the negative Hyper Emotions linked to this current generation. Thus it is certainly useful to focus on creating a method to expand the Hyper Emotion happiness by reducing the game’s level of competitiveness. This can ultimately lead to therapeutic clinics that utilize Uno as a way to mitigate the stresses associated with generation Z.